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Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells

cAMP-dependent protein kinase (PKAc) is a pivotal signaling protein in eukaryotic cells. PKAc has two well-characterized regulatory subunit proteins, RI and RII (each having α and β isoforms), which keep the PKAc catalytic subunit in a catalytically inactive state until activation by cAMP. Previous...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Haushalter, Kristofer J., Casteel, Darren E., Raffeiner, Andrea, Stefan, Eduard, Patel, Hemal H., Taylor, Susan S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868259/
https://ncbi.nlm.nih.gov/pubmed/29378851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809988
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