Cardiac ischemia-reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα

Type I PKA regulatory α-subunit (RIα; encoded by the Prkar1a gene) serves as the predominant inhibitor protein of the catalytic subunit of cAMP-dependent protein kinase (PKAc). However, recent evidence suggests that PKA signaling can be initiated by cAMP-independent events, especially within the con...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Haushalter, Kristofer J., Schilling, Jan M., Song, Young, Sastri, Mira, Perkins, Guy A., Strack, Stefan, Taylor, Susan S., Patel, Hemal H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962616/
https://ncbi.nlm.nih.gov/pubmed/31674811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00237.2019
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