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Structural Basis of Analog Specificity in PKG I and II
Cyclic GMP analogs, 8-Br, 8-pCPT, and PET-cGMP, have been widely used for characterizing cellular functions of cGMP-dependent protein kinase (PKG) I and II isotypes. However, interpreting results obtained using these analogs has been difficult due to their low isotype specificity. Additionally, each...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896746/ https://ncbi.nlm.nih.gov/pubmed/28793191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00369 |
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