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Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus

In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. This mutant couldn’t grow in the absence of MVA. However, after a long lag-phase of 4–6 days the mutant adapted from auxotrophic to prototrophic phenotype. During t...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Reichert, Sebastian, Ebner, Patrick, Bonetti, Eve-Julie, Luqman, Arif, Nega, Mulugeta, Schrenzel, Jacques, Spröer, Cathrin, Bunk, Boyke, Overmann, Jörg, Sass, Peter, François, Patrice, Götz, Friedrich
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052127/
https://ncbi.nlm.nih.gov/pubmed/30050520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01539
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