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The Mevalonate Auxotrophic Mutant of Staphylococcus aureus Can Adapt to Mevalonate Depletion

In this study, we attempted to adopt the auxotrophic mevalonate synthase mutant (ΔmvaS mutant) of Staphylococcus aureus to study whether a nongrowing but viable cell population is tolerant to bactericidal antibiotics. The mevalonate-depleted nongrowing ΔmvaS mutant was found tolerant to antibiotics....

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Detalhes bibliográficos
Main Authors: Yu, Wenqi, Leibig, Martina, Schäfer, Tina, Bertram, Ralph, Ohlsen, Knut, Götz, Friedrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811321/
https://ncbi.nlm.nih.gov/pubmed/23959312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00726-13
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