Daptomycin Tolerance in the Staphylococcus aureus pitA6 Mutant Is Due to Upregulation of the dlt Operon

Understanding the mechanisms of how bacteria become tolerant toward antibiotics during clinical therapy is a very important object. In a previous study, we showed that increased daptomycin (DAP) tolerance of Staphylococcus aureus was due to a point mutation in pitA (inorganic phosphate transporter)...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Mechler, Lukas, Bonetti, Eve-Julie, Reichert, Sebastian, Flötenmeyer, Matthias, Schrenzel, Jacques, Bertram, Ralph, François, Patrice, Götz, Friedrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862447/
https://ncbi.nlm.nih.gov/pubmed/26883712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03022-15
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