Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus

Rhodomyrtone (Rom) is an acylphloroglucinol antibiotic originally isolated from leaves of Rhodomyrtus tomentosa. Rom targets the bacterial membrane and is active against a wide range of Gram-positive bacteria but the exact mode of action remains obscure. Here we isolated and characterized a spontane...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Nguyen, Minh-Thu, Saising, Jongkon, Tribelli, Paula Maria, Nega, Mulugeta, Diene, Seydina M., François, Patrice, Schrenzel, Jacques, Spröer, Cathrin, Bunk, Boyke, Ebner, Patrick, Hertlein, Tobias, Kumari, Nimerta, Härtner, Thomas, Wistuba, Dorothee, Voravuthikunchai, Supayang P., Mäder, Ulrike, Ohlsen, Knut, Götz, Friedrich
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547885/
https://ncbi.nlm.nih.gov/pubmed/31191485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01157
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