Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus

Rhodomyrtone (Rom) is an acylphloroglucinol antibiotic originally isolated from leaves of Rhodomyrtus tomentosa. Rom targets the bacterial membrane and is active against a wide range of Gram-positive bacteria but the exact mode of action remains obscure. Here we isolated and characterized a spontane...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Nguyen, Minh-Thu, Saising, Jongkon, Tribelli, Paula Maria, Nega, Mulugeta, Diene, Seydina M., François, Patrice, Schrenzel, Jacques, Spröer, Cathrin, Bunk, Boyke, Ebner, Patrick, Hertlein, Tobias, Kumari, Nimerta, Härtner, Thomas, Wistuba, Dorothee, Voravuthikunchai, Supayang P., Mäder, Ulrike, Ohlsen, Knut, Götz, Friedrich
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547885/
https://ncbi.nlm.nih.gov/pubmed/31191485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01157
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