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The Current State and Future of CRISPR-Cas9 gRNA Design Tools
Recent years have seen the development of computational tools to assist researchers in performing CRISPR-Cas9 experiment optimally. More specifically, these tools aim to maximize on-target activity (guide efficiency) while also minimizing potential off-target effects (guide specificity) by analyzing...
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| Pubblicato in: | Front Pharmacol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052051/ https://ncbi.nlm.nih.gov/pubmed/30050439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00749 |
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