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Following the electrons: Peculiarities in the catalytic cycles of Radical SAM enzymes

Radical SAM enzymes use S-adenosyl-L-methionine as an oxidant to initiate radical-mediated transformations that would otherwise not be possible with Lewis acid/base chemistry alone. These reactions are either redox neutral or oxidative leading to certain expectations regarding the role of SAM as eit...

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Bibliografiske detaljer
Udgivet i:Nat Prod Rep
Main Authors: Ruszczycky, Mark W., Zhong, Aoshu, Liu, Hung-wen
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051909/
https://ncbi.nlm.nih.gov/pubmed/29485151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7np00058h
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