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Copper-catalyzed oxidative cross-dehydrogenative coupling of 2H-chromenes and terminal alkynes

An efficient copper-catalyzed cross-dehydrogenative coupling of 2H-chromenes and terminal alkynes mediated by DDQ has been established. Protic additive EtOH proved to be crucial to harmonizing the oxidation with subsequent alkynylation step by retaining the oxidation state of oxocarbenium ion in the...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Yang, Fei, Li, Yangshan, Floreancig, Paul E., Li, Xiaoyan, Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051884/
https://ncbi.nlm.nih.gov/pubmed/29963678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00949j
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