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FM19G11 inhibits O(6)‐methylguanine DNA‐methyltransferase expression under both hypoxic and normoxic conditions
FM19G11 is a small molecular agent that inhibits hypoxia‐inducible factor‐1‐alpha (HIF‐1α) and other signaling pathways. In this study, we characterized the modulating effects of FM19G11 on O(6)‐methylguanine DNA‐methyltransferase (MGMT), the main regulator of temozolomide (TMZ) resistance in gliobl...
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| Publicat a: | Cancer Med |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051152/ https://ncbi.nlm.nih.gov/pubmed/29761922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1551 |
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