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Hybrid TiO(2)-ruthenium nano-photosensitizer synergistically produces reactive oxygen species in both hypoxic and normoxic conditions

Photodynamic therapy (PDT) is widely used to treat diverse diseases, but its dependence on oxygen to produce cytotoxic reactive oxygen species (ROS) diminishes the therapeutic effect in a hypoxic environment such as solid tumors. Here, we developed a ROS-producing hybrid nanoparticle-based photosens...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Gilson, Rebecca C., Black, Kvar C.L., Lane, Daniel D., Achilefu, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749187/
https://ncbi.nlm.nih.gov/pubmed/28667692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201704458
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