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FM19G11 inhibits O(6)‐methylguanine DNA‐methyltransferase expression under both hypoxic and normoxic conditions
FM19G11 is a small molecular agent that inhibits hypoxia‐inducible factor‐1‐alpha (HIF‐1α) and other signaling pathways. In this study, we characterized the modulating effects of FM19G11 on O(6)‐methylguanine DNA‐methyltransferase (MGMT), the main regulator of temozolomide (TMZ) resistance in gliobl...
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| Publicado no: | Cancer Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051152/ https://ncbi.nlm.nih.gov/pubmed/29761922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1551 |
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