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Automated Removal of Phospholipids from Membrane Proteins for H/D Exchange Mass Spectrometry Workflows
Membrane proteins are currently the most common targets for pharmaceuticals. However, characterization of their structural dynamics by hydrogen/deuterium exchange mass spectrometry (HDX-MS) is sparse due to insufficient automated methods to handle full-length membrane proteins in lipid bilayers. Add...
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| Publicado en: | Anal Chem |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6050989/ https://ncbi.nlm.nih.gov/pubmed/29723469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b00429 |
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