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Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry

The study of membrane protein structure and enzymology has traditionally been hampered by the inherent insolubility of membrane proteins in aqueous environments and experimental challenges in emulating an in vivo lipid environment. Phospholipid bilayer nanodiscs have recently been shown to be of gre...

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Main Authors: Hebling, Christine M., Morgan, Christopher R., Stafford, Darrel W., Jorgenson, James W., Rand, Kasper D., Engen, John R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895417/
https://ncbi.nlm.nih.gov/pubmed/20518534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac100962c
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