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Metabolic Imaging of the Human Brain with Hyperpolarized (13)C Pyruvate Demonstrates (13)C Lactate Production in Brain Tumor Patients

Hyperpolarized (HP) magnetic resonance imaging using [1-13C] pyruvate is a novel method that can characterize energy metabolism in the human brain and brain tumors. Here we present the first dynamically acquired human brain HP 13C metabolic spectra and spatial metabolite maps in cases of both untrea...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Miloushev, Vesselin Z., Granlund, Kristin L., Boltyanskiy, Rostislav, Lyashchenko, Serge K., DeAngelis, Lisa M., Mellinghoff, Ingo K., Brennan, Cameron W., Tabar, Vivian, Yang, T. Jonathan, Holodny, Andrei I., Sosa, Ramon E., Guo, YanWei W., Chen, Albert P., Tropp, James, Robb, Fraser, Keshari, Kayvan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050093/
https://ncbi.nlm.nih.gov/pubmed/29769199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0221
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