Metabolic Imaging of the Human Brain with Hyperpolarized (13)C Pyruvate Demonstrates (13)C Lactate Production in Brain Tumor Patients

Hyperpolarized (HP) magnetic resonance imaging using [1-13C] pyruvate is a novel method that can characterize energy metabolism in the human brain and brain tumors. Here we present the first dynamically acquired human brain HP 13C metabolic spectra and spatial metabolite maps in cases of both untrea...

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Библиографические подробности
Опубликовано в: :Cancer Res
Главные авторы: Miloushev, Vesselin Z., Granlund, Kristin L., Boltyanskiy, Rostislav, Lyashchenko, Serge K., DeAngelis, Lisa M., Mellinghoff, Ingo K., Brennan, Cameron W., Tabar, Vivian, Yang, T. Jonathan, Holodny, Andrei I., Sosa, Ramon E., Guo, YanWei W., Chen, Albert P., Tropp, James, Robb, Fraser, Keshari, Kayvan R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050093/
https://ncbi.nlm.nih.gov/pubmed/29769199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0221
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