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Metabolic Imaging in the Anesthetized Rat Brain Using Hyperpolarized [1-(13)C] Pyruvate and [1-(13)C] Ethyl Pyruvate

Formulation, polarization, and dissolution conditions were developed to obtain a stable hyperpolarized solution of [1-(13)C]-ethyl pyruvate. A maximum tolerated concentration and injection rate were determined, and (13)C spectroscopic imaging was used to compare the uptake of hyperpolarized [1-(13)C...

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Bibliografische gegevens
Hoofdauteurs: Hurd, Ralph E., Yen, Yi-Fen, Mayer, Dirk, Chen, Albert, Wilson, David, Kohler, Susan, Bok, Robert, Vigneron, Daniel, Kurhanewicz, John, Tropp, James, Spielman, Daniel, Pfefferbaum, Adolf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890241/
https://ncbi.nlm.nih.gov/pubmed/20432284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22364
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