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Metabolic Imaging in the Anesthetized Rat Brain Using Hyperpolarized [1-(13)C] Pyruvate and [1-(13)C] Ethyl Pyruvate
Formulation, polarization, and dissolution conditions were developed to obtain a stable hyperpolarized solution of [1-(13)C]-ethyl pyruvate. A maximum tolerated concentration and injection rate were determined, and (13)C spectroscopic imaging was used to compare the uptake of hyperpolarized [1-(13)C...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890241/ https://ncbi.nlm.nih.gov/pubmed/20432284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22364 |
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