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In vivo investigation of cardiac metabolism in the rat using MRS of hyperpolarized [1-(13)C] and [2-(13)C]pyruvate
Hyperpolarized (13)C MRS allows the in vivo assessment of pyruvate dehydrogenase complex (PDC) flux, which converts pyruvate to acetyl-coenzyme A (acetyl-CoA). [1-(13)C]pyruvate has been used to measure changes in cardiac PDC flux, with demonstrated increase in (13)C-bicarbonate production after dic...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838505/ https://ncbi.nlm.nih.gov/pubmed/23904148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3003 |
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