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Quantitation of In Vivo Metabolic Kinetics of Hyperpolarized Pyruvate in Rat Kidneys using Dynamic (13)C Magnetic Resonance Spectroscopic Imaging
With signal-to-noise ratio enhancements on the order of 10,000-fold, hyperpolarized MR spectroscopic imaging (MRSI) of metabolically active substrates allows the study of both the injected substrate and downstream metabolic products in vivo. Although hyperpolarized [1-(13)C]-pyruvate, in particular,...
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Autori principali: | , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169748/ https://ncbi.nlm.nih.gov/pubmed/21538639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1719 |
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