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Quantitation of In Vivo Metabolic Kinetics of Hyperpolarized Pyruvate in Rat Kidneys using Dynamic (13)C Magnetic Resonance Spectroscopic Imaging

With signal-to-noise ratio enhancements on the order of 10,000-fold, hyperpolarized MR spectroscopic imaging (MRSI) of metabolically active substrates allows the study of both the injected substrate and downstream metabolic products in vivo. Although hyperpolarized [1-(13)C]-pyruvate, in particular,...

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Dettagli Bibliografici
Autori principali: Xu, Tao, Mayer, Dirk, Gu, Meng, Yen, Yi-Fen, Josan, Sonal, Tropp, James, Pfefferbaum, Adolf, Hurd, Ralph, Spielman, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169748/
https://ncbi.nlm.nih.gov/pubmed/21538639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1719
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