Dynamic metabolic imaging of hyperpolarized [2-(13)C]pyruvate using spiral CSI with alternating spectral band excitation

PURPOSE: In contrast to [1-(13)C]pyruvate, hyperpolarized [2-(13)C]pyruvate permits the ability to follow the (13)C label beyond flux through pyruvate dehydrogenase complex and investigate the incorporation of acetyl-CoA into different metabolic pathways. However, chemical shift imaging (CSI) with [...

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Main Authors: Josan, Sonal, Hurd, Ralph, Park, Jae Mo, Yen, Yi-Fen, Watkins, Ron, Pfefferbaum, Adolf, Spielman, Daniel, Mayer, Dirk
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849119/
https://ncbi.nlm.nih.gov/pubmed/23878057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24871
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