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lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures
Attenuation of pre-rRNA synthesis in response to elevated temperature is accompanied by increased levels of PAPAS (“promoter and pre-rRNA antisense”), a long noncoding RNA (lncRNA) that is transcribed in an orientation antisense to pre-rRNA. Here we show that PAPAS interacts directly with DNA, formi...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Genes Dev |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Cold Spring Harbor Laboratory Press
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049515/ https://ncbi.nlm.nih.gov/pubmed/29907651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.311688.118 |
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