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Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex

SF3b1 is an essential component of the U2 snRNP implicated in branch site (BS) recognition and found to be frequently mutated in several human cancers. While recent structures of yeast and human SF3b1 have revealed its molecular architecture, the importance of specific RNA:protein contacts and confo...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Carrocci, Tucker J., Paulson, Joshua C., Hoskins, Aaron A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049509/
https://ncbi.nlm.nih.gov/pubmed/29752352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065664.118
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