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A Potential Role for U2AF-SAP 155 Interactions in Recruiting U2 snRNP to the Branch Site

Base pairing between U2 snRNA and the branchpoint sequence (BPS) is essential for pre-mRNA splicing. Because the metazoan BPS is short and highly degenerate, this interaction alone is insufficient for specific binding of U2 snRNP. The splicing factor U2AF binds to the pyrimidine tract at the 3′ spli...

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Bibliografiske detaljer
Main Authors: Gozani, Or, Potashkin, Judith, Reed, Robin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109061/
https://ncbi.nlm.nih.gov/pubmed/9671485
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