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U4 snRNA nucleolar localization requires the NHPX/15.5-kD protein binding site but not Sm protein or U6 snRNA association

All small nuclear RNAs (snRNAs) of the [U4/U6.U5] tri-snRNP localize transiently to nucleoli, as visualized by microscopy after injection of fluorescein-labeled transcripts into Xenopus laevis oocyte nuclei. Here, we demonstrate that these RNAs traffic to nucleoli independently of one another, becau...

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Hlavní autoři: Gerbi, Susan A., Borovjagin, Anton V., Odreman, Federico E., Lange, Thilo Sascha
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172826/
https://ncbi.nlm.nih.gov/pubmed/12939253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200301071
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