Identification of novel snRNA-specific Sm proteins that bind selectively to U2 and U4 snRNAs in Trypanosoma brucei

In eukaryotes the seven Sm core proteins bind to U1, U2, U4, and U5 snRNAs. In Trypanosoma brucei, Sm proteins have been implicated in binding both spliced leader (SL) and U snRNAs. In this study, we examined the function of these Sm proteins using RNAi silencing and protein purification. RNAi silen...

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Main Authors: Tkacz, Itai Dov, Lustig, Yaniv, Stern, Michael Zeev, Biton, Moshe, Salmon-Divon, Mali, Das, Anish, Bellofatto, Vivian, Michaeli, Shulamit
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1705756/
https://ncbi.nlm.nih.gov/pubmed/17105994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.174307
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