Llwytho...

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells

Loss of excitatory amino acid transporters (EAATs) has been implicated in a number of human diseases including spinocerebellar ataxias, Alzhiemer’s disease and motor neuron disease. EAAT4 and GLAST/EAAT1 are the two predominant EAATs responsible for maintaining low extracellular glutamate levels and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Perkins, Emma M, Clarkson, Yvonne L, Suminaite, Daumante, Lyndon, Alastair R, Tanaka, Kohichi, Rothstein, Jeffrey D, Skehel, Paul A, Wyllie, David J A, Jackson, Mandy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049029/
https://ncbi.nlm.nih.gov/pubmed/29741614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy169
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!