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Real-time dynamics of mutagenesis reveal the chronology of DNA repair and damage tolerance responses in single cells

Evolutionary processes are driven by diverse molecular mechanisms that act in the creation and prevention of mutations. It remains unclear how these mechanisms are regulated because limitations of existing mutation assays have precluded measuring how mutation rates vary over time in single cells. To...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Hovedforfatter: Uphoff, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048535/
https://ncbi.nlm.nih.gov/pubmed/29941584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801101115
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