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Real-time dynamics of mutagenesis reveal the chronology of DNA repair and damage tolerance responses in single cells

Evolutionary processes are driven by diverse molecular mechanisms that act in the creation and prevention of mutations. It remains unclear how these mechanisms are regulated because limitations of existing mutation assays have precluded measuring how mutation rates vary over time in single cells. To...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Uphoff, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048535/
https://ncbi.nlm.nih.gov/pubmed/29941584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801101115
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