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Single-molecule motions and interactions in live cells reveal target search dynamics in mismatch repair
MutS is responsible for initiating the correction of DNA replication errors. To understand how MutS searches for and identifies rare base-pair mismatches, we characterized the dynamic movement of MutS and the replisome in real time using superresolution microscopy and single-molecule tracking in liv...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687589/ https://ncbi.nlm.nih.gov/pubmed/26575623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507386112 |
| Oznake: |
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