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Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair
The ability of proteins to locate specific targets among a vast excess of nonspecific DNA is a fundamental theme in biology. Basic principles governing these search mechanisms remain poorly understood, and no study has provided direct visualization of single proteins searching for and engaging targe...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494904/ https://ncbi.nlm.nih.gov/pubmed/23012240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211364109 |
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