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Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair

The ability of proteins to locate specific targets among a vast excess of nonspecific DNA is a fundamental theme in biology. Basic principles governing these search mechanisms remain poorly understood, and no study has provided direct visualization of single proteins searching for and engaging targe...

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Bibliografiset tiedot
Päätekijät: Gorman, Jason, Wang, Feng, Redding, Sy, Plys, Aaron J., Fazio, Teresa, Wind, Shalom, Alani, Eric E., Greene, Eric C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494904/
https://ncbi.nlm.nih.gov/pubmed/23012240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211364109
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