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Single-molecule motions and interactions in live cells reveal target search dynamics in mismatch repair

MutS is responsible for initiating the correction of DNA replication errors. To understand how MutS searches for and identifies rare base-pair mismatches, we characterized the dynamic movement of MutS and the replisome in real time using superresolution microscopy and single-molecule tracking in liv...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Liao, Yi, Schroeder, Jeremy W., Gao, Burke, Simmons, Lyle A., Biteen, Julie S.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687589/
https://ncbi.nlm.nih.gov/pubmed/26575623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507386112
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