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Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase

The role of water in oxime-mediated reactivation of phosphylated cholinesterases (ChEs) has been asked with recurrence. To investigate oximate water structure changes in this reaction, reactivation of paraoxon-inhibited human acetylcholinesterase (AChE) was performed by the oxime asoxime (HI-6) at d...

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Vydáno v:Biosci Rep
Hlavní autoři: Zueva, Irina V., Lushchekina, Sofya V., Masson, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048214/
https://ncbi.nlm.nih.gov/pubmed/29773682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180609
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