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Oxime-Mediated Reactivation of Organophosphate-Inhibited Acetylcholinesterase with Emphasis on Centrally-Active Oximes

This review provides an overview of the global research leading to the large number of compounds developed as reactivators of acetylcholinesterase inhibited by a variety of organophosphate compounds, most of which are nerve agents but also some insecticides. A number of these organophosphates are hi...

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Bibliografische gegevens
Gepubliceerd in:Neuropharmacology
Hoofdauteurs: Chambers, Janice E., Dail, Mary B., Meek, Edward C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492440/
https://ncbi.nlm.nih.gov/pubmed/32544483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108201
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