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Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates
Current oxime reactivators for organophosphate-inhibited cholinesterase (ChE) do not effectively cross the blood–brain barrier and therefore cannot restore brain ChE activity in vivo. Our laboratories have studied highly relevant sarin and VX surrogates, which differ from their respective nerve agen...
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| Publicado no: | Ann N Y Acad Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940271/ https://ncbi.nlm.nih.gov/pubmed/27153507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13053 |
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