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Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes
INTRODUCTION: Organophosphorus nerve agents inhibit the enzyme, acetylcholinesterase (AChE; EC 3.1.1.7). AChE reactivators (also known as oximes) are generally used for the reactivation of an inhibited enzyme. METHODS: Two new AChE reactivators—K033 and K027—were tested for theirin vitro reactivatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3550075/ https://ncbi.nlm.nih.gov/pubmed/18072133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF03161181 |
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