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Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro

We have evaluated in vitro the potency of 23 oximes to reactivate human erythrocyte acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE) inhibited by racemic leptophos-oxon (O-[4-bromo-2,5-dichlorophenyl]-O-methyl phenyl-phosphonate), a toxic metabolite of the pesticide leptophos. Com...

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Detalhes bibliográficos
Main Authors: Jun, Daniel, Musilova, Lucie, Pohanka, Miroslav, Jung, Young-Sik, Bostik, Pavel, Kuca, Kamil
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996742/
https://ncbi.nlm.nih.gov/pubmed/21152278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11082856
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