Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro

We have evaluated in vitro the potency of 23 oximes to reactivate human erythrocyte acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE) inhibited by racemic leptophos-oxon (O-[4-bromo-2,5-dichlorophenyl]-O-methyl phenyl-phosphonate), a toxic metabolite of the pesticide leptophos. Com...

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Bibliografiska uppgifter
Huvudupphovsmän: Jun, Daniel, Musilova, Lucie, Pohanka, Miroslav, Jung, Young-Sik, Bostik, Pavel, Kuca, Kamil
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Diversity Preservation International (MDPI) 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996742/
https://ncbi.nlm.nih.gov/pubmed/21152278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11082856
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