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Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro

We have evaluated in vitro the potency of 23 oximes to reactivate human erythrocyte acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE) inhibited by racemic leptophos-oxon (O-[4-bromo-2,5-dichlorophenyl]-O-methyl phenyl-phosphonate), a toxic metabolite of the pesticide leptophos. Com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jun, Daniel, Musilova, Lucie, Pohanka, Miroslav, Jung, Young-Sik, Bostik, Pavel, Kuca, Kamil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996742/
https://ncbi.nlm.nih.gov/pubmed/21152278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11082856
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