The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats

BACKGROUND: The aim of our study was to compare the ability of two combinations of oximes (HI-6 + trimedoxime and HI-6 + K203) with atropine to counteract acute sarin-induced brain damage with the efficacy of antidotal treatment involving single oxime (HI-6) and atropin using in vivo methods. METHOD...

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Udgivet i:BMC Pharmacol Toxicol
Main Authors: Caisberger, Filip, Pejchal, Jaroslav, Misik, Jan, Kassa, Jiri, Valis, Martin, Kuca, Kamil
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022407/
https://ncbi.nlm.nih.gov/pubmed/29954446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0227-0
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