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Ontogeny of SERT Expression and Antidepressant-like Response to Escitalopram in Wild-Type and SERT Mutant Mice

Depression is a disabling affective disorder for which the majority of patients are not effectively treated. This problem is exacerbated in children and adolescents for whom only two antidepressants are approved, both of which are selective serotonin reuptake inhibitor (SSRIs). Unfortunately SSRIs a...

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Détails bibliographiques
Publié dans:J Pharmacol Exp Ther
Auteurs principaux: Mitchell, Nathan C., Gould, Georgianna G., Koek, Wouter, Daws, Lynette C.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047222/
https://ncbi.nlm.nih.gov/pubmed/27288483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.233338
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