Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function.

Depression is a major health problem for which most patients are not effectively treated. This problem is further compounded in children and adolescents where only two antidepressants [both selective serotonin reuptake inhibitors (SSRIs)] are currently approved for clinical use. Mouse models prov...

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Main Authors: Nathan C Mitchell, Georgianna G Gould, Corey M Smolik, Wouter eKoek, Lynette C Daws
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-10-01
Colecção:Frontiers in Pharmacology
Assuntos:
Adolescent
antidepressant
serotonin transporter
juvenile
selective serotonin reuptake inhibitor
tricyclic
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00131/full
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