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Antidepressant-like effects and basal immobility depend on age and serotonin transporter genotype

Monoamine uptake inhibitors are common treatments for depression; however, the therapeutic efficacy of these drugs varies widely. Two factors that are commonly linked to clinical outcome are age and serotonin transporter (SERT) genotype. Mouse models provide powerful tools to study consequences of a...

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Detalhes bibliográficos
Publicado no:Genes Brain Behav
Main Authors: Mitchell, Nathan C., Koek, Wouter, Daws, Lynette C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710348/
https://ncbi.nlm.nih.gov/pubmed/26250357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12238
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