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Serotonin Transporter and Plasma Membrane Monoamine Transporter Are Necessary for the Antidepressant-Like Effects of Ketamine in Mice

Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great interest in findings that low doses of ketamine, a non-competitive N-methyl-...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Bowman, Melodi A., Vitela, Melissa, Clarke, Kyra M., Koek, Wouter, Daws, Lynette C.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589995/
https://ncbi.nlm.nih.gov/pubmed/33066466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207581
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