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Serotonin Transporter and Plasma Membrane Monoamine Transporter Are Necessary for the Antidepressant-Like Effects of Ketamine in Mice

Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great interest in findings that low doses of ketamine, a non-competitive N-methyl-...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bowman, Melodi A., Vitela, Melissa, Clarke, Kyra M., Koek, Wouter, Daws, Lynette C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589995/
https://ncbi.nlm.nih.gov/pubmed/33066466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207581
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