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Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children

Organic cation transporter 1 (OCT1) plays an important role in the disposition of clinically important drugs, and the capacity of OCT1 activity is presumed to be proportional to the protein expression level in organ tissues. Knowledge of OCT1 protein expression in children, especially neonates and s...

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Publicado en:Drug Metab Dispos
Autores principales: Hahn, David, Emoto, Chie, Vinks, Alexander A., Fukuda, Tsuyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047210/
https://ncbi.nlm.nih.gov/pubmed/27780835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.072256
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