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Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children

Organic cation transporter 1 (OCT1) plays an important role in the disposition of clinically important drugs, and the capacity of OCT1 activity is presumed to be proportional to the protein expression level in organ tissues. Knowledge of OCT1 protein expression in children, especially neonates and s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Metab Dispos
Hauptverfasser: Hahn, David, Emoto, Chie, Vinks, Alexander A., Fukuda, Tsuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047210/
https://ncbi.nlm.nih.gov/pubmed/27780835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.072256
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