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On the Mechanism of Action of Dragmacidins I and J, Two New Representatives of a New Class of Protein Phosphatase 1 and 2A Inhibitors

[Image: see text] Two new brominated bis(indole) alkaloids, dragmacidins I (1) and J (2), showing low micromolar cytostatic activity, along with three known congeners were isolated from the Tanzanian sponge Dragmacidon sp. and their structures determined by the analysis of their NMR and MS data. Fro...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Cruz, Patricia G., Martínez Leal, Juan Fernando, Daranas, Antonio Hernández, Pérez, Marta, Cuevas, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045348/
https://ncbi.nlm.nih.gov/pubmed/30023878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01786
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