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Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
[Image: see text] In this study, we apply a battery of molecular similarity techniques to known inhibitors of kynurenine 3-monooxygenase (KMO), querying each against a repository of approved, experimental, nutraceutical, and illicit drugs. Four compounds are assayed against KMO. Subsequently, diclof...
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| Pubblicato in: | ACS Omega |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2018
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044753/ https://ncbi.nlm.nih.gov/pubmed/30023839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b02091 |
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