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Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury
Acute kidney injury (AKI) following ischemia–reperfusion injury (IRI) has a high mortality and lacks specific therapies. Here, we report that mice lacking kynurenine 3-monooxygenase (KMO) activity (Kmo(null) mice) are protected against AKI after renal IRI. We show that KMO is highly expressed in the...
Gorde:
| Argitaratua izan da: | Exp Mol Med |
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| Egile Nagusiak: | , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374422/ https://ncbi.nlm.nih.gov/pubmed/30760699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0210-x |
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