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Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma
OBJECTIVES: In pancreatic ductal adenocarcinoma (PDAC) patients, increased expression of proinflammatory neurotrophic growth factors (e.g. nerve growth factor (NGF)) correlates with a poorer prognosis, perineural invasion (PNI) and, with regard to NGF, pain severity. We hypothesized that NGF sequest...
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| Izdano u: | Pancreas |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044729/ https://ncbi.nlm.nih.gov/pubmed/29975347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001090 |
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